Chung Laboratory · Houston Methodist

Discovering how genes shape neurological disease.

The Chung Lab investigates how mitochondrial dynamics and glial lipid metabolism shape nervous system function and contribute to neurological disease.

Hyung-Lok Chung, Ph.D.

Assistant Professor (Tenure-Track) · Principal Investigator, Chung Lab

Director, Drosophila Functional Genomics Core

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Conceptual illustration of a myelinated neuron, a supporting glial cell, and lipid-like forms.

Chung Lab

Mechanisms of neurological disease

Independent research into how genes and cellular pathways influence nervous system health.

Glia & lipid metabolism

How lipid metabolism and signaling connect glial function with neuronal health and neuroinflammation.

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Mitochondrial dynamics

How Cdk8/CDK19 regulates mitochondrial fission and contributes to neurological disease.

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Drosophila Core

Functional genomics & collaboration

Scientific expertise and customized experiments for your research questions.

  • Rare disease genetics
  • Functional studies of human variants
  • Customized fly models & experiments
  • Consultation & project quotes

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Directed by Hyung-Lok Chung, Ph.D.

Recent publications

New insights from our collaborative work

Genetics in Medicine · 2026

CDK19 variants and neurodevelopmental disorders

Integrating clinical genetics with in vivo evidence to interpret rare variants.

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Genetics in Medicine Open · 2026

DDX23 gain of function

Linking functional changes in DDX23 to a neurodevelopmental phenotype.

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HGG Advances · 2026

MARK2 and nervous system development

Identifying loss-of-function variants associated with neurodevelopmental disorder.

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All publications

People & mentorship

Mentorship beyond the lab

We support trainees as they grow through research and mentorship, and celebrate the next steps our alumni take in medicine and higher education.

Andrew Kim

Former Research Technician I

Medical Student

Baylor College of Medicine

Sarita Palacio

Former Rice Research Intern

Medical Student

UTMB

Weihan (Lily) Chen

Former SURI Research Intern

Undergraduate Student

Harvard University

Meet our alumni

Discovery is a team effort.

We welcome researchers and trainees who are curious about genetics, cell biology, and neuroscience. Learn about our community and contact us to discuss research opportunities.

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